Layton R.H., Payapilli J., Ma T., Murphy T.H., Smirnova N., Langley B.C., Sultana R., Butterfield D.A., Santagata S., Gazaryan I., Bell G.W., and Ratan R.R. (2010) Refining the “peroxide code”: spatial, temporal and quantitative regulation of hydrogen peroxide in astrocytes induces non-cell-autonomous protection of neurons via a novel Nrf-2-independent pathway. PNAS 107(40):17385-90, 2010.
Liu RR, Brown CE, and Murphy TH (2007) Differential regulation of cell proliferation in neurogenic zones in mice lacking cystine transport by xCT. Biochem Biophys Res Commun 364:528-533.
Shih AY, Erb H, and Murphy TH (2007) Dopamine activates Nrf2-regulated neuroprotective pathways in astrocytes and meningeal cells. J Neurochem 101:109-119.
Shih AY, Erb H, Sun X, Toda S, Kalivas PW, and Murphy TH (2006) Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. J Neurosci 26:10514-10523.
Sun X, Shih AY, Johannssen HC, Erb H, Li P, and Murphy TH (2006) Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface. J Biol Chem 281:17420-17431.
Shih AY, Li P, and Murphy TH (2005a) A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. J Neurosci 25:10321-10335.
Shih AY, Imbeault S, Barakauskas V, Erb H, Jiang L, Li P, Murphy TH (2005b) Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. J Biol Chem 280:22925-22936.
Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, Johnson JA, Murphy TH (2003) Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci 23:3394-3406.
Murphy TH, Miyamoto M, Sastre A, Schnaar RL, Coyle JT (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2:1547-1558.